Dr. Annie Shapiro, another American, is introduced in 16.082. Stratt points her out to Grace, saying she the inventor of “a new kind of DNA splicing that’s now called the Shapiro method.”

As narrator, Grace later (17.103) describes Shapiro as “the world’s smartest and most accomplished microbiologist”.

Grace finds out he’s going to be training both Shapiro and DuBois. Shapiro is to be DuBois’s counterpart on the backup crew.

In contrast to DuBois’s meticulous notes, Shapiro’s are described as “sloppy” (17.082).

In 17.088, DuBois declares that he and Shapiro “have begun a sexual relationship”.

In Chapter 21, there is a massive explosion in the research center at Baikonur and Stratt realizes DuBois and Shapiro were both scheduled to be there experimenting on Astrophage. It is soon confirmed that they both died in the explosion.

In Chapter 23, Shapiro is mentioned again and for the last time in the context of the eventual explanation of how the explosion occurred.

Shapiro’s direct speech consists of 8 quoted passages, 65 tokens, and 52 unique words.

She doesn’t say any words that are exclusive to her but she is the only person other than the narrator to use the words ‘exercise’, ‘teeth’, ‘pee’, or ‘floating’.